Medical Studies

Part One: Fascinating article published in Jan 2010 in the Journal of Bone and Joint Surgery on the problems associated with failure of MoM hip replacements.

Part Two: Early failure of MoM bearings in hip resurfacing and large-diameter hip replacement/Jrnl of Bone and Joint Surgery, Jan 2010

Part Three: Early Failure of MoM bearings in Hip Resurfacing and large-diameter hip replacement/Jrnl of Bone and Joint Surgery, Jan 2010.

Using MRI’s with an optimized protocol to detect metal debris by Hollis Potter MD http://accordent02.origindigital.net/dmn/NOV18MARS_Archive/main.htm

Nice metal-on-metal round table discussion with 4 orthopedic surgeons: Pros and cons discussed.

Case Report in the Journal of Bone and Joint Surgery


Additional Information on Complications Associated with Hip Arthroplasty.

Metal ion analysis post hip resurfacing: guidance for surgeons- published in 2010

Podium and poster presentations at the March 2010 American Association of Orthopedic Surgeons reviewed size, design and position of the implant cups to determine critical factors leading to metal ion release and other complications of hip surgery.

Acute and chronic systemic chromium toxicity

Systemic distribution of wear debris after hip replacement. A cause for concern?

Continuing Medical Education Panel sponsored by the American Orthopedics Association for Surgeons: Total hip Atheroplasty: Is there a MOM bearings controversy? Part One of Five

Continuing Medical Education Panel sponsored by the American Orthopedics Association for Surgeons: Total hip Atheroplasty: Is there a MOM bearings controversy? (Part Two of Five)

Continuing Medical Education Panel sponsored by the American Orthopedics Association for Surgeons: Total hip Atheroplasty: Is there a MOM bearings controversy? (Part Three of Five)

Continuing Medical Education Panel sponsored by the American Orthopedics Association for Surgeons: Total hip Atheroplasty: Is there a MOM bearings controversy? (Part Four of Five

 Continuing Medical Education Panel sponsored by the American Orthopedics Association for Surgeons: Total hip Atheroplhttp://www.mydepuyhiprecall.com/2011/02/cancer-risk-after-metal-on-metal-and.htmlasty: Is there a MOM bearings controversy? (Part Five of Five)


Cobalt Toxicity in Two hip Replacement Patients


Key Metal Toxicity Abstracts (batch one/ 1-14)

Total hip replacement and cancer. A cohort study. (Ion toxicity abstracts 1 of 14.)

 Cancer risk after hip replacement with metal implants: a population-based cohort study in Sweden. (Ion Toxicity studies 2 of 14)


Cancer risk after metal on metal and polyethylene on metal total hip arthroplasty. (Ion Toxicity series 3 of 14)

Cancer risk after metal on metal and polyethylene on metal total hip arthroplasty. (Ion Toxicity series 3 of 14)

Elevated serum cobalt with metal-on-metal articulating surfaces. (Ion txicity series 4 of 14)

Cobalt and chromium concentrations in patients with metal on metal total hip replacements. (Ion Toxicity 5 of 14)

Cobalt and chromium concentrations in patients with metal-on-metal and other cementless total hip arthroplasty. (Ion Toxicity 6 of 14)

Cobalt and chromium concentrations in patients with metal-on-metal and other cementless total hip arthroplasty. (Ion Toxicity/7 of 14)

Serum and urine metal levels in patients with metal-on-metal surface arthroplasty. (Ion toxicity 8 of 14)

Metal degradation products: a cause for concern in metal-metal bearings? (Ion toxicity 9 of 14)

Tissue reaction to metal on metal total hip prostheses. (ion Toxicity 10 of 14)

Systemic metal-protein binding associated with total joint replacement arthroplasty. (Ion toxicity 11 of 14)

A triple assay technique for the evaluation of metal-induced, delayed-type hypersensitivity responses in patients with or receiving total joint arthroplasty. (Ion toxcity 12 of 14)

 Metal sensitivity in patients with orthopaedic implants. (Ion Toxicity 13 of 14)

Orthopaedic implant related metal toxicity in terms of human lymphocyte reactivity to metal-protein complexes produced from cobalt-base and titanium-base implant alloy degradation. (ion Toxicity 14 of 14)

Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. (Ion Toxicity)

What seems to be the bottom line in the 14 or 15 Ion Toxicity research abstracts printed over the last 7 days?

Acute and chronic systemic chromium toxicity (1 of 8 on Chromium toxicity)

Investigations on the nephrotoxicity and hepatotoxicity of trivalent and hexavalent chromium compounds (2 of 8 on Chromium toxicity).

The toxicology of chromium with respect to its chemical speciation: a review. (3 of 8 chromium toxicology)

Essential elements as early indicators of hexavalent chromium nephrotoxicity. (4 of 8 Chromium toxicity)

Toxic effects of chromium and its compounds. (5 of 8 Chromium Toxicity)

Estimates of the chromium(VI) reducing capacity in human body compartments as a mechanism for attenuating its potential toxicihttp://www.mydepuyhiprecall.com/2011/04/allergy-testing-for-depuy-hip-implant.htmlty and carcinogenicity. (6 of 8 Chromium Toxicity)

Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000. (7 of 8 Chromium toxicity)

Selected toxicological aspects of chromium(VI) compounds. (chromium toxicity 8 of 8)


Comments on Postmortem study of femoral osteolysis associated with metal-on-metal articulation in total hip replacement: an analysis of nine cases.


Allergy testing for the Depuy Hip Implant patients?


Nine-Year Incidence of Kidney Disease in Patients Who Have had Total Hip Arthroplasty.

Early Markers of Nephrotoxicity[kidney toxicity] in Patients With Metal-on-metal Hip Arthroplasty.

Silent soft tissue pathology is common with a modern metal-on-metal hip arthroplasty.

Large Diameter Metal on Metal Bearing Total Hip Replacements

Helpful consolidated ion toxicity numbers, 1-2 years post op for MOM large femoral head implants

Interesting research re the MOM hip issues: Chromium 3 vs Chromium 6?

Induction of apoptosis and necrosis by metal ions in vitro.


Additional study done post mortem illustrating Asymptomatic Osteolysis after Death

Great discussion on video in 2005 re the issues surrounding the the Depuy hip and issues hip early on

Interesting X rays of hip issues with Artheroplasty

Surprising statement from older (2004) Journal Article

Progress in understanding the implications of systemic effects of MOM and poly implants?

MRI of asymptomatic patients with metal-on-metal and polyethylene-on-metal total hip arthroplasties.

Metal-on-metal bearings: THE EVIDENCE SO FAR

Does early intervention prevent bone/soft tissue loss: What is the outcome of revision surgery?

Do we know the threshold for revision surgery? (2of 7)

Is there an accepted cut-off level for blood metal ion levels? (3 of 7)

What is the significance of Gender with the Metal on Metal hips (4 of 7)

What is the frequency of adverse metal reactions with the MoM hips? (5 of 7)

What do plain radiographs, ultrasound, MRI and CT offer the Depuy hip patient (6 of 7)

Systemic effects of metal debris (7a of 7)

Systemic effects of metal debris (7b of 7)

Systemic effects of metal debris (7c of 7)

Systemic effects of metal debris (7d of 7)

Systemic effects of metal debris (7e of 7); excerpts from the committee on Mutagneicity

Systemic effects of metal debris (7f of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7g of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7g of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7h of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7i of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7j of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7k of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7L of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7M of 7); excerpts from the Committee on Mutagenicity

Systemic effects of metal debris (7N of 7); excerpts from the Committee on Mutagenicity

Possible Cobalt Toxicity reported in 2 patients with the Depuy hip

Development of hematopoietic cancers after implantation of total joint replacement.

Quantification of t(14;18) in the lymphocytes of healthy adult humans as a possible biomarker for environmental exposures to carcinogens.

The association between metal ions from hip resurfacing and reduced T-cell counts

Mayo Clinic studies the squeaky-ceramic hip problem

Review of the Cell biology surrounding metal on metal hips (1 of x in a series)

Review of the Cell biology surrounding metal on metal hips (2 of x in a series)

Review of the Cell biology surrounding metal on metal hips (3 of x in a series)

Review of the Cell biology surrounding metal on metal hips (4 of x in a series)

Review of the Cell biology surrounding metal on metal hips (5 of x in a series)

Review of the Cell biology surrounding metal on metal hips (6 of x in a series)

Review of the Cell biology surrounding metal on metal hips (7 of x in a series)

Review of the Cell biology surrounding metal on metal hips (8 of x in a series)

Review of the Cell biology surrounding metal on metal hips (9 of x in a series)

Chromium 3 results in permanent modification to DNA in MoM hips. (1 of 6.) What does this mean?

Research questions re Chromium 3

Chromium 3 results in permanent modification to DNA in MoM hip? (2 of 6.) What does this mean?

Chromium 3 results in permanent modification to DNA in MoM hip? (3 of 6.) What does this mean?

Chromium 3 results in permanent modification to DNA in MoM hip? (4 and 5 of 6.) What does this mean?

Chromium 3 results in permanent modification to DNA in MoM hip? (6 of 6.) What does this mean?

Early markers of nephrotoxicity in patients with metal-on-metal hip arthroplasty

Chromium induced Genotoxicity with BOTH Chromium 3 and Chromium 6

MRI After Arthroplasty: Comparison of MAVRIC and Conventional Fast Spin-Echo Techniques

Comparison of surgical outcomes and implant wear between ceramic-ceramic and ceramic-polyethylene articulations in total hip arthroplasty

Effect of chromium and cobalt ions on primary human lymphocytes in vitro

Effects of metal-on-metal wear on the host immune system and infection in hip arthroplasty.

New insights into wear and biological effects of metal-on-metal bearings.

Polyethylene and metal wear particles: characteristics and biological effects.

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (1of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (2of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (3of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (4of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (5of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (6 of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (7 of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (8 of x)

Reviewing the historical Journal literature for publications discussing Cancer risk associated with joint/hip implants (9 of 9)

Oxidative stress induced cancers: Is the trivalent chromium really oxidized hexavalent chromium? (1 of x)

Oxidative stress induced cancers: Is the trivalent chromium really oxidized hexavalent chromium? (2 of x)

Oxidative stress induced cancers: Is the trivalent chromium really oxidized hexavalent chromium? (3 of x)

Sensitivity and specificity of blood cobalt and chromium metal ions for predicting failure of metal-on-metal hip replacement.

Effects of Cobalt Nanoparticles on Human T Cells In Vitro.

Cutaneous and systemic hypersensitivity reactions to metallic implants

Cytogenetic analysis by chromosome painting. (a series 2 of x)

Evidence for a possible need for Cytogenic testing with Depuy hips or MoM hips (3 of x)

FISH and Depuy hip testing in the future for carcinogens? (series 4 of x)

Is the FISH technology cost effective? (series 5 of x)

Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells.

California Technology Assessment Forum (CTAF) Requested to Reveiw Evidence for MoM resurfacing systems

Preliminary observations on possible premalignant changes in bone marrow adjacent to worn total hip arthroplasty implants

New Study published on the Corail Pinnalce-First study to report wear rates of these hips post explant

A patient centered approach to the Depuy hip recall? What?...only in England.

Hip Replacement Devices are All the Same, Study Says

Accelerating failure rate of the ASR total hip replacement: 6 year post surgical rate of 48.8%

Metal hip lubricant reduces wear and tear: study

New Hip Implant Discovery - (Second article...con't from yesterday's post)

More on DNA changes with Chromium and Cobalt

More DNA studies with nanoparticles such as Chromium and Cobalt and the possiblity of limiting the systemic damage from such particles (Part Two)

More Medical studies oin the Chromium and Cobalt causing DNA damage

Lymph node affectations after hip replacements in the medical literature

Post Hip Replacement Results considering Activity levels

Results post revision surgery

Ceramic bearings for total hip arthroplasty have high survivorship at 10 years.

What parts are replaced in a revsion?

Exchanging only the femoral head in a revsion surgery.

Anyone have a bone graft during revision surgery?

Revision rates after total joint replacement

Another Hypothesis on the cause of Pseudotumors associated with MoM hips

Evidence that there is no differentitation long term re effectives of one bearing surface over another in hip replacements! what?

Seeking information.......Granulomas, histiocytosis, type IV immune response....

So what is the cause of these pseudotumors after the second revision? (part 2 of x in this series)

Granuloma journal articles provided to my medical Team related to the hip (7 of x)

Interesting finding on a new Pseudotumor study just published

How safe are metal-on-metal hip implants?/confidential Depuy memo from 2005 discussing the potential carcinogenic properties of these metals

Response to the British Orthodpedic Association's Release questioning the link between Cancer and the metal hips

Bristol Hip Meeting 2011 in England: interesting comments

Recent Data from the Hip registries in England and Wales: Metal-on-metal stemmed articulations give poor implant survival compared with other options and should not be implanted

A counter point to the recent metal on metal warnings for large diameter hips>: Do they result in low or high revision rates? Should they be used or shouldn't they?

Who said there were no suspicions surrounding these metal-on metal hips until late? Not so.

Metal ion levels decrease after revision for metallosis arising from large-diameter metal-on-metal hip arthroplasty

Interesting finding on the occurance of pseudotumors in well funtioning MOM hips

Looking at blood, urine and plasma levels of Cr and Co metals post artheroplasty

Risk of cancer in first seven years after metal-on-metal hip replacement compared with other bearings and general population: linkage study between the National Joint Registry of England and Wales and hospital episode statistics

Severe cobalt intoxication following hip replacement revision: Clinical features and outcome.

Histopathology of localised adverse reactions to metal debris (ARMD) seen in association with failed metal on metal (MoM) hip arthroplasties

MRI imaging of the post op hip

Pathology Findings on Femoral Heads.......discovered post surgery.

Survey Participation requested by Dr. Tom Joyce's group at New Castle University in England: Patient experiences with the Depuy Hip and others.....

How safe are metal-on-metal hip implants?

Advances in carcinogenic metal toxicity and potential molecular markers. (1 of x in a series)

Advances in metal-induced oxidative stress and human disease. (2 of x in a series)

Oxidative Stress process associated with Metal on metal hips (series 3 of x)

Oxidative Stress process associated with Metal on metal hips (series 4 of x)

A great pictorial to illustrate the metal on metal oxidation process (5 of 5 in a series)

Measuring Cr and Cobalt levels in the organs.

Low Molecular weight antioxidants are capable of chelating metal ions like Chromium and cobalt

Evidence-Based Understanding of Management Perils for Metal-on-Metal Hip Arthroplasty Patients.

How safe are metal-on-metal hip implants?

Differential distribution of cobalt, chromium, and nickel between whole blood, plasma and urine in patients after metal-on-metal (mom) hip arthroplasty.

Yet another similarity between A new model of Carcinogenesis and the processes used to describe metal induced interacelluar effects

Is it Chromium or Cobalt that is the biggest culpret in metalosis?

The Financial Impact of Joint Registries in Identifying Poorly Performing Implants

High incidence of pseudotumour formation after large-diameter metal-on-metal total hip replacement: A prospective cohort study.

Systemic Coblat ion effects following MoM hip replacement

Presence of Cobalt and Chromium Ions in the Seminal Fluid of Young Patients With Metal-on-Metal Total Hip Arthroplasty.

Cobalt metabolism and toxicology-A brief update.

Yet another study seeing potential long term toxic effects of the Metal on metal hip

Case Report: High Chromium and Cobalt Levels in a Pregnant Patient with Bilateral Metal-on-Metal Hip Arthroplasties.

Thresholds for indirect DNA damage across cellular barriers for orthopaedic biomaterials

Synovial Sarcoma with a metal on poly hip replacement

Causes and High Incidence of Early Hip Replacement Failure

Timing of Acute Myocardial Infarction in Patients Undergoing Total Hip or Knee ReplacementA Nationwide Cohort Study

Why should you use an MARS MRI protocal when following hips?

Cobalt metabolism and toxicology-A brief update.

Oxidative Stress drives tumor progression and metastasis

Another way to deal with oxidative stress which is generated with hip revision surgery

Molecular and immune toxicity of CoCr nanoparticles in MoM hip arthroplasty.

Local and systemic toxicity of nanoscale debris particles in total hip arthroplasty.

Hip artroplasty: A transient reason not to be pregnant.

Aseptic Lymphocyte Dominated Vasculitis-Associated Lesion Resulting From Trunnion Corrosion in a Cobalt-Chrome Unipolar Hemiarthroplasty

Ion levels poor indicator for hip arthroplasty debris

Variability in Costs Associated with Total Hip and Knee Replacement Implants.

Alcohol Use in Elective Total Hip Arthroplasty: Risk or Benefit?

Acupuncture Reduces Hip Surgery Pain - New Research

Stem cell-powered implant set to revolutionise orthopaedic surgery

Hip Resrufacing results of 10 year survival statistics

 Measuring Cancer risk 4 years post implant with MOM hips

To all of us glucosamine Chondroitin users: Looks like there is some benefit afterall!

 More confirmation of the generation of free radicals and oxidative stress causing Cellular dysfuction from MoM implants

More on Nanoparticles causing DNA damage from MOM hips with oxidative stress ( 1 of x in a series)

Quantifiable Lymphocytic reactivity to metals can develop in 1-4 years after MOM hip revisions in asymptomatic patients

survival rates of hip resurfacing after 10 years

Frequency of adverse reaction to MoM biomet hip sees low adverse reactions

No elevation of metal ion levels in the breast milk of young patient with MOM hip replacement

The Epidemiology of Revision Total Hip Arthroplasty in the United States

Cementless Metaphyseal Fitting Anatomic Total Hip Arthroplasty with a Ceramic-on-Ceramic Bearing in Patients Thirty Years of Age or Younger

More on Nanoparticles causing DNA damage from MOM hips with oxidative stress ( 2 of x in a series)

Simultaneous bilaterial hip replacements/resurfacing vs two -stage proceedures : 2 studies

More on Nanoparticles causing DAN damage from MOM hips with Oxidatve stress (3 of x in a series)

10 year survival rates of Birmingham hip

Long-term results, durability, modularity among advantages of metal-on-metal hips

A new mass reported following MoM resurfacing

Follow up on patients under 30 with Ceramic-on- Ceramic hips

Ceramic-on-metal hip bearings show less wear, friction than all-metal hip bearings

Study Finds Elevated Levels of Cobalt and Chromium in Offspring of Patients With Metal-On-Metal Hip Implants

MRI Findings in Painful Metal-on-Metal Hip Arthroplasty

DNA Damage to Embrioys in Zebrafish from Cobalt exposure

More on Nanoparticles causing DNA damage from MOM hips throught oxidatve stress (4 of x in a series)

Mortality and implant revision rates of hip arthroplasty in patients with osteoarthritis: registry based cohort study

More on Nanoparticles causing DNA damage from MOM hips throught oxidatve stress (5 of x in a series)

Metal-On-Metal Hip Implants-a Technology Overview by the American Academy of Orthopaedic Surgeons ( 1 of x)

Studies needed to look at survivorship with All hip replacement surgeries

Metal release from hip prostheses: cobalt and chromium toxicity and the role of the clinical laboratory

Choosing a Bearing Material for Hip Arthroplasty: Commentary on an article by Ingrid MiloŇ°ev, PhD, et al.: “Comparison of Ten-Year Survivorship of Hip Prostheses with Use of Conventional Polyethylene, Metal-on-Metal, or Ceramic-on-Ceramic Bearings”

More on Nanoparticles causing DNA damage from MOM hips through oxidatve stress (6 of x in a series)

Metal ions may lead to the generation of free radicals

Nanoparticles' indirect threat to DNA : Toxic Gossip?

Mini-symposium: the hip: (v) Simulation and measurement of wear in metal-on-metal bearings in vitro- understanding the reasons for increased wear

Low revision rate after total hip arthroplasty in patients with pediatric hip diseases

Australian National Registry Reports Staggering 44% Revision Rate of DePuy ASR XL Hip Implants

More on Nanoparticles causing DNA damage from MOM hips through oxidatve stress (7 of 7 in a series/final post in this series)

Metal-on-Metal Total Hip Arthroplasty: Do Symptoms Correlate with MR Imaging Findings?

Failure rates of metal-on-metal hip resurfacings: analysis of data from the National Joint Registry for England and Wales

The risk of revision due to dislocation after total hip arthroplasty depends on surgical approach, femoral head size, sex, and primary diagnosis.

Revision Surgery is overestimated in hip revisions

The hard lesson of metal-on-metal hip implants.

Cobalt poisoning due to metal-on-metal hip implants

Metal-on-Metal Total Hip Resurfacing Arthroplasty: An Evidence-Based Analysis (2006)

Bearing Surfaces for Hip Arthroplasty- Is Metal-on-metal a Passing Fancy?

Cost-effectiveness of total hip arthroplasty versus resurfacing arthroplasty: economic evaluation alongside a clinical trial.

Renal perforation due to the migration of metal cerclage in hip arthroplasty

Metal-on-metal hips: cobalt can induce an endotoxin-like response

Hip fracture trials do not include enough patients with dementia

Cementless Modular Total Hip Arthroplasty in Patients Younger than Fifty with Femoral Head Osteonecrosis: Minimum Fifteen-Year Follow-Up

Case Report of complete wear-through of metal-backed component

Hip Resurfacing is less painful at 24hours post surgery

Cobalt Intoxication following a revision with Ceramic-on ceramic

Cementless Modular Total Hip Arthroplasty in Patients Younger than Fifty with Femoral Head Osteonecrosis: Minimum Fifteen-Year Follow-Up

Case Report of complete wear-through of metal-backed component

Hip Resurfacing is less painful at 24hours post surgery

Cobalt Intoxication following a revision with Ceramic-on ceramic

Lymphocytic reactivity to metals lag increases in metal ion levels

The Withdrawn ASR™ THA and Hip Resurfacing Systems: How Have Our Patients Fared Over 1 to 6 Years?

Hip resurfacing revisions vs total hip revisions vs partial hip revisions: what are the differences in the outcomes?

Do Ion Concentrations after Metal-on-Metal Hip Resurfacing Increase Over Time

comparing ceramic-on-metal and metal-on-metal outcomes

Leg-Length Discrepancy After Revision Hip Arthroplasty: Are Modular Stems Superior?

Metal-on-metal joint bearings and hematopoetic malignancy.

Prevalence of pseudotumor in asymptomatic patients after metal-on-metal hip arthroplasty.

Newcastle University researchers find explanation for pain in people with metal on metal hip joints

Delayed sciatic nerve palsy following resurfacing hip arthroplasty caused by metal debris.

MR Imaging of Metal-on-Metal Hip Prostheses

Caution advised for rheumatoid arthritis patients considering hip or knee replacement

MR Imaging Plays Key Role in Post-Op Metal-on-Metal Hip Arthroplasty

comments from an MD invovled with Cobalt Related issues with his hip

Arthroprosthetic cobaltism: identification of the at-risk patient.

Arthroprosthetic cobaltism and cardiomyopathy

Researchers set safe upper limit metal ion levels for metal-on-metal hip resurfacings

Metal-on-Metal vs Conventional Total Hip Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Metallosis-induced Iliopsoas Bursal Cyst Causing Venous Obstruction and Lower-limb Swelling After Metal-on-metal THA

Consider both imaging and symptoms before metal-on-metal hip arthroplasty revisions

CoCrMo metal-on-metal hip replacements.

Serum cobalt and chromium levels elevated after metal disc arthroplasty

Genetic and Epigenetic Mechanisms in metal carcinogenesis (1 of x in a series)

Genetic and Epigenetic Mechanisms in metal carcinogenesis (2 of x in a series)

Genetic and Epigenetic Mechanisms in metal carcinogenesis (3of x in a series)

Genetic and Epigenetic Mechanisms in metal carcinogenesis (4 of x in a series)

Genetic and Epigenetic Mechanisms in metal carcinogenesis (5 of x in a series)

MRI Predicts ALVAL and Tissue Damage in Metal-on-Metal Hip Arthroplasty

Genetic and Epigenetic Mechanisms in metal carcinogenesis (6 of 6 in a series)

Study suggests women have higher risk of hip implant failure

Outpatient toxicology clinic experience of patients with hip implants *

Primary Metal-on-Metal Hip Arthroplasty was not associated with Increased Cancer Risk

Metal allergy in patients with total hip replacement: A review

Taking Another Look at Osteolysis

 Acetabular bone loss in revision total hip arthroplasty: evaluation and management.

Are the concerns regarding metal-on-metal total hip arthroplasties founded in 2012?

Bone restoration and grafting..a common occurance in planning for revision surgeries

The Results of Metal-On-Metal Hip Resurfacing in Patients Under 30 Years of Age.

Metal Ions Point to MoM Hip Failure

Tissue damage causes unexplained pain among metal-on-metal hip implant patients

Metal-on-Metal Hip Implant Pain Linked to Tissue Damage, Study Shows

The clinical implications of elevated blood metal ion concentrations in asymptomatic patients with MoM hip resurfacings: a cohort study

Pseudotumour Formation Due to Tribocorrosion at the Taper Interface of Large Diameter Metal on Polymer Modular Total Hip Replacements.

Bisphosphonates associated with improved hip, knee implant survival

Study: Neuraxial Anesthesia Better for Hip, Knee Arthroplasty

Metal Ions Activate Vascular Endothelial Cells and Increase Lymphocyte Chemotaxis and Binding.

Tissue damage from metal-on-metal hip implants appears before pain symptoms appear

Aspirin Post Hip Replacement OK for Extended Prophylaxis

 Adverse local tissue reaction arising from corrosion at the femoral neck-body junction in a dual-taper stem with a cobalt-chromium modular neck.

Commentary and Perspective on the Stryker implants