"Although the affects of metal ions in maternal and fetal subjects are unknown, the fact that the placenta is not a complete barrier to the transport of these metals is noteworthy," said Joshua J. Jacobs, MD, Professor and Chairman of Orthopaedic Surgery at Rush University Medical Center in Chicago. "As metal-on-metal implants increase in popularity and use, especially among young, active patients, women of child-bearing age and their doctors should be aware of these findings when considering their hip replacement implant options."
- Mothers with MoM implants and their offspring had elevated Chromium and cobalt levels compared to the cohort without metal implants.
- A correlation existed between maternal and infant cobalt and chromium levels in the Implant Group, while the Control Group showed no correlation.
- Offspring of women with MoM implants had about half the levels of cobalt in their bloodstream as their mothers and approximately 15 percent of their mother's chromium levels, while there was no significant difference among ion levels between mothers and infants in the Control Group.
- There was no statistically significant differences in levels of titanium or nickel among any of the cohorts.