This new test was the Cytogenitics test based on the research done on finding translocations in hip patients.
Background on this topic can be found here:
Summary of the Systemic issues dicussed from 7a-7n/14 articles considered by the committee on mutagenicity
Quantification of t(14;18) in the lymphocytes of healthy adult humans as a possible biomarker for environmental exposures to carcinogens.
Evidence for a possible need for Cytogenic testing with Depuy hips or MoM hips (3 of x)
Detection of T (14;18) translocations in pheripheral blood lymphcytes in patients with total hip ateroplasty
Note: I have to review this with someone who understands the research test. I can give you the answer I got but I have to talk to someone about the test methodology. We ran these tests on the Ovarian tissues that was removed not on a sample from blood lymphocytes so again, this is preliminary.
- The FISH analysis is negative for the ALK gene arrangement in all of teh cells analyzed.
- The FISH analysis with the probe specific for the (14;18) translocation was performed on 400 interphase nuclei. There was no t (14;18) rearrangement detected.
- There were signals detected on two hybridizations with the 3p14.2 detected.