Now, at the time I wrote the preface for that study, I noted a few things below.
-"patients who have undergone joint replacement have a higher than normal incidence of DNA damage to blood lymphocytes. In concentrations found in the blood after hip replacement, cobalt and chromium have the ability to signal across intact barriers in the body and cause irreversible DNA changes to cells on the other side of the barrier
So why am I raising this again? It is not the banking of femoral heads for the purpose of bone grafting that was of interest to me but the following :
Our findings indicate that, even with a detailed medical history and careful physical examination, clinically important diseases including neoplasms and Paget's disease are observed in patients diagnosed with osteoarthritis prior to total hip arthroplasty...105 of 6161 femoral heads demonstrated abnormal or reactive histopathological features not reported prior to surgery. A retrospective review of the histopathological findings was conducted to evaluate and reclassify all previous observations of abnormalities. Nineteen patients had a suspected neoplasm. Of these nineteen, eight cases of non-Hodgkin's lymphoma or chronic lymphocytic leukemia and one case of myelodysplastic syndrome were confirmed on further investigation. One subsequently confirmed malignancy was detected per 770 femoral heads examined.
Histological examination plays an integral role in quality assurance in femoral head banking, and it also represents a possible early diagnostic test for bone and bone-marrow-related diseases in patients undergoing total hip arthroplasty
As the article above in the link pointed out, hip patients are not routinely screened for cancer. It is likely that a targeted screening programme would identify more patients with cancer than were identified here."