Department of Pathology, University hospital of North Tees and Hartlepool NHS Foundation Trust, UK.
- 17 cases showed metallosis
- 60 cases showed chronic lymphocytic sinovitis***
- 40 cases showed lymphoid aggregates* with germinal centers**
*Lymphoid aggregates appear as slightly elevated nodules that may be normal in color or more red than the surrounding tissue. Sometimes they can look like small polyps. This is a harmless, non- cancerous condition.
**Germinal centers (or germinal centres; GC) are sites within lymph nodes (also within lymph nodules in peripheral lymph tissues) where mature B lymphocytes rapidly proliferate, differentiate, mutate their antibodies (through somatic hypermutation), and class switch their antibodies during a normal immune response to an infection.
***Synovitis is the medical term for inflammation of the synovial membrane. This membrane lines joints which possess cavities, known as synovial joints. The condition is usually painful, particularly when the joint is moved. The joint usually swells due to synovial fluid collection