Sunday, October 23, 2011
Cytogenetic analysis by chromosome painting. (a series 2 of x)
This is the second in a series on the chromosome painting which is a test that is used to determine genetic damage. See the prior post to understand why we are discussing this topic.
Essentially, there is a question about long term systemic effects of chromosome aberrations in bone-marrow cells adjacent to the prosthesis at revision surgery. This test is a means to identify those aberrations. I will have more details on this in the coming weeks but it is my understanding that changes in these chromosomes may not be seen for 10-20 years.
I don't think there have been enough studies to substantiate much but there are two studies that have shown significantly higher rate of chromosomal aberration in local bone-marrow cells adjacent to the hip.
Cytometry. 1994 Mar 15;18(1):2-10.
Posted by Connie at 5:27 PM