Genotoxic issues surrounding systemic effects of metal debris (continued from prior posts)
The committee on mutagenicity has reported that internal exposure to orthopedic metals is associated with increased genotoxicity.
This is a series of commentary from the committee on mutangenicity evidence based on the the key journal articles examined by that committee. I think you will find the results really interesting if you are concerned about the systemic effects of the metal.
5th piece of evidence reviewed by the committee:
Urinary 8-hydroxydeoxyguanosine and sister chromatid exchanges in patients with total hip replacements.
SourceDepartment of Occupational Medicine, University of Vienna, Austria. firstname.lastname@example.org
- While the test was adequately conducted, there was insufficient information on the interpretatoion of the assay data.
- no conclusion could be drawn with respect to metal specifica mtuagenic effects from these data.