1. Concern remains about the long-term effect of raised metal ions and systemic dissemination which can be divided into two types of long term systemic effects: immune mediated and genotoxic.
2. Changes in the lymphocyte counts have been reported in patients with MoM hip implants.
[added by Connie: lymphocytes are responsible for fighting infection or foreign substances that might be harmful to the body. So at a high level, these lymphocytes are part of the immune system and they remove foreign substances from the blood, organs, tissues and lymph nodes.]
[I am inserting the full reference (46) below because I found it fascinating----- A test is available to measure the absolute number of circulating lymphocytes for MoM patients vs a control group. So why wouldn't you get this count prior to surgery in order to measure the circulating lymphocytes pre and post surgery. The person who would order this is an Immunologist. I never thought about talking to an immunologist. They can perform tests that are Microbiological cultures, histopathologic examinations, and immunohistochemical analysis.]